I'm trying to think of all the 'Lenny and his eye problem' gags from the show. If anyone can think of more, feel free to add.
*In 'Tis the Fifteenth Season':
Homer (giving Lenny the photo cube): I filed down the photo cube so you don't hurt your eyes. (Pokes Lenny's eyes)
Lenny: Wow! It only stings a little!
*'Three Gays of the Condo:
Homer is delusional and tries to fit Lenny into the puzzle:
Lenny: My eyes! [My doctor says (?)] I'm not supposed to get jigs in them!
Also, this may or may not be from the show, I might be dreaming, Lenny says something about not getting nuts in his eyes?